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Qin Zhang Selected Research

nirogacestat

3/2015PEST domain mutations in Notch receptors comprise an oncogenic driver segment in triple-negative breast cancer sensitive to a γ-secretase inhibitor.
6/2014Comparison of dynamic contrast-enhanced MR, ultrasound and optical imaging modalities to evaluate the antiangiogenic effect of PF-03084014 and sunitinib.
3/2013Synergistic effect of the γ-secretase inhibitor PF-03084014 and docetaxel in breast cancer models.
9/2012Biomarker and pharmacologic evaluation of the γ-secretase inhibitor PF-03084014 in breast cancer models.

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Qin Zhang Research Topics

Disease

197Neoplasms (Cancer)
06/2024 - 06/2005
58Inflammation (Inflammations)
04/2024 - 03/2004
41Infections
06/2024 - 08/2003
30Neoplasm Metastasis (Metastasis)
07/2024 - 11/2011
30Fibrosis (Cirrhosis)
12/2023 - 01/2005
25Breast Neoplasms (Breast Cancer)
03/2024 - 09/2012
22Wounds and Injuries (Trauma)
12/2023 - 10/2005
21Hepatocellular Carcinoma (Hepatoma)
04/2024 - 06/2006
21Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
11/2023 - 02/2015
18Pain (Aches)
03/2024 - 07/2010
16Burns
08/2023 - 02/2004
15Hypoxia (Hypoxemia)
01/2024 - 07/2018
15Lung Neoplasms (Lung Cancer)
11/2023 - 01/2005
15Colorectal Neoplasms (Colorectal Cancer)
11/2023 - 09/2006
14Type 2 Diabetes Mellitus (MODY)
05/2024 - 05/2012
14Sepsis (Septicemia)
03/2024 - 06/2010
14Ischemia
03/2024 - 10/2010
14Stomach Neoplasms (Stomach Cancer)
01/2024 - 08/2005
13Carcinogenesis
12/2023 - 08/2007
12Body Weight (Weight, Body)
02/2024 - 01/2006
12Stroke (Strokes)
01/2024 - 01/2007
12Insulin Resistance
10/2023 - 10/2005
11Sarcopenia
05/2024 - 01/2014
11Obesity
03/2024 - 03/2002
11Chronic Obstructive Pulmonary Disease (COPD)
02/2024 - 01/2021
11Ovarian Neoplasms (Ovarian Cancer)
12/2023 - 08/2012
11Adenocarcinoma of Lung
05/2023 - 03/2018
11Non-alcoholic Fatty Liver Disease
12/2022 - 03/2010
10Hemorrhage
12/2023 - 08/2011
10Heart Failure
11/2023 - 10/2006
10Hypertension (High Blood Pressure)
06/2023 - 07/2008
9Rheumatoid Arthritis
03/2024 - 01/2016
9Esophageal Squamous Cell Carcinoma
01/2024 - 01/2018
9Mitochondrial Diseases (Mitochondrial Disease)
08/2023 - 03/2010
9Alzheimer Disease (Alzheimer's Disease)
06/2023 - 01/2018
9Autoimmune Diseases (Autoimmune Disease)
01/2022 - 02/2019
8Chronic Hepatitis B
04/2024 - 09/2008
8Cardiovascular Diseases (Cardiovascular Disease)
04/2024 - 03/2011
8Neural Tube Defects (Exencephaly)
02/2024 - 06/2013
8Hyperglycemia
09/2023 - 10/2005
8Cognitive Dysfunction
04/2023 - 06/2021
8Fatty Liver
01/2023 - 10/2008
8Reperfusion Injury
01/2022 - 01/2012
7Liver Cirrhosis (Hepatic Cirrhosis)
04/2024 - 01/2013
7Dysbiosis
01/2024 - 09/2020
7Melanoma (Melanoma, Malignant)
12/2023 - 06/2021
7Systemic Lupus Erythematosus (Libman-Sacks Disease)
07/2023 - 12/2017
7Experimental Arthritis
04/2023 - 11/2019
7Necrosis
01/2023 - 04/2011
7Carcinoma (Carcinomatosis)
01/2022 - 12/2011
6Uterine Cervical Neoplasms (Cancer of the Cervix)
07/2024 - 08/2012
6Prostatic Neoplasms (Prostate Cancer)
04/2024 - 04/2019
6Epilepsy (Aura)
01/2024 - 04/2008

Drug/Important Bio-Agent (IBA)

70Proteins (Proteins, Gene)FDA Link
07/2024 - 10/2005
63Biomarkers (Surrogate Marker)IBA
05/2024 - 09/2012
28Messenger RNA (mRNA)IBA
01/2024 - 03/2006
23MicroRNAs (MicroRNA)IBA
11/2023 - 10/2012
22CytokinesIBA
04/2024 - 09/2010
16LipidsIBA
03/2024 - 05/2012
16EnzymesIBA
03/2024 - 11/2004
16Therapeutic UsesIBA
02/2024 - 03/2004
16Glucose (Dextrose)FDA LinkGeneric
10/2023 - 01/2014
16RNA (Ribonucleic Acid)IBA
05/2023 - 03/2004
14Long Noncoding RNAIBA
03/2024 - 01/2018
14Immune Checkpoint InhibitorsIBA
02/2024 - 10/2020
13DNA (Deoxyribonucleic Acid)IBA
04/2024 - 06/2006
13Insulin (Novolin)FDA Link
11/2023 - 10/2005
13Phosphotransferases (Kinase)IBA
04/2023 - 10/2005
12Anti-Bacterial Agents (Antibiotics)IBA
04/2022 - 02/2004
11Histones (Histone)IBA
12/2023 - 06/2013
11Oxygen (Dioxygen)IBA
11/2023 - 10/2012
10HydrogelsIBA
04/2024 - 04/2008
10Indicators and Reagents (Reagents)IBA
01/2024 - 09/2015
10CollagenIBA
12/2023 - 08/2011
9Transcription Factors (Transcription Factor)IBA
07/2024 - 06/2005
8PolymersIBA
07/2024 - 05/2016
8LigandsIBA
03/2024 - 03/2010
8Triglycerides (Triacylglycerol)IBA
01/2024 - 01/2012
8Cisplatin (Platino)FDA LinkGeneric
01/2024 - 03/2009
8DexmedetomidineFDA Link
12/2023 - 06/2015
8Interleukin-6 (Interleukin 6)IBA
12/2023 - 01/2013
8Sirtuin 1IBA
12/2023 - 01/2016
8Antiviral Agents (Antivirals)IBA
11/2023 - 01/2012
8AntioxidantsIBA
12/2022 - 01/2006
8VaccinesIBA
01/2021 - 04/2007
7Paclitaxel (Taxol)FDA LinkGeneric
03/2024 - 01/2018
7InflammasomesIBA
01/2024 - 08/2019
7GhrelinIBA
10/2023 - 10/2010
7AntigensIBA
10/2021 - 10/2014
7AntibodiesIBA
08/2021 - 01/2016
6LipopolysaccharidesIBA
03/2024 - 08/2010

Therapy/Procedure

95Therapeutics
04/2024 - 08/2003
34Drug Therapy (Chemotherapy)
01/2024 - 02/2011
26Immunotherapy
03/2024 - 01/2018
21Radiotherapy
11/2023 - 04/2009
13Chinese Traditional Medicine (Traditional Chinese Medicine)
04/2024 - 03/2004
13Photothermal Therapy
01/2023 - 11/2014
12Lasers (Laser)
03/2024 - 05/2014
8Length of Stay
12/2023 - 08/2012
7Transplantation
01/2023 - 05/2006